20 Best-Selling Face Serums Broken Down by Cost Per Wear

Shopping for skincare is one of our absolute favorite pastimes—face serums, especially. They're one of the most strategic ways to enhance and customize our glow routine, effortlessly stacking and boosting the benefits we're already getting from our other staples like cleansers, creams, and masks. While shopping for pretty much any kind of serum gets our adrenaline pumping in the best way possible, we're especially exhilarated by best-selling face serums everyone and their mother is dying to get their complexion on.

Call us superficial, but we want something that's effective and results-driven, yes, but also covetable and brimming with holy-grail potential, which is where one of our all-time favorite beauty retailers, Dermstore, comes in. Boasting every type of beauty product imaginable (from hair to skincare to makeup), it's one of our first stops whenever we're in the market for top-quality new finds that are high on the industry's most-wanted list. The store carries everything from professional-strength formulas you'll likely only find at the dermatologist's office to niche spa, specialty, and natural beauty brands hailing from all around the world. Not surprisingly, it has an amazing collection of best-selling face serums as well.

Since everyone has different goals and concerns when it comes to the wellness of both our skin and bank account, we decided to dissect the top 20 best-selling face serums you can buy on Dermstore's website right now—breaking each formula down by its benefits, ingredients, and cost per wear. (We're guestimating each small bottle will last roughly three months but realize this might fluctuate.) Ahead, 20 best-selling face serums everyone wants from Dermstore and how much they'll cost you per application. (We're starting our countdown with the retailer's 20th bestseller, so make sure to scroll all the way down to see which holy grail serum took the number one spot!)

#20

Treats: fine lines and wrinkles, loss of firmness, dullness, environmental damage

Key ingredients: peptides, vitamin E, antioxidants

Cost per wear: $70 ÷ 90 wears (three months, once daily in the evening) = $0.78 per wear

#19

Treats: dryness, dullness, fine lines and wrinkles, environmental damage

Key ingredients: hyaluronic acid, ceramides, niacinamide

Cost per wear: $115 ÷ 180 wears (three months, twice daily) = $0.64 per wear

#18

Treats: loss of firmness, fine lines and wrinkles, environmental damage, pH disruption

Key ingredients: bamboo, coconut oil, coconut water, plant stem cells, natural retinol alternative complex

Cost per wear: $62 ÷ 180 wears (three months, twice daily) = $0.34 per wear

#17

Treats: dullness, dehydration, cell build-up and congestion, loss of firmness and plumpness, fine lines and wrinkles, environmental damage, uneven skin texture

Key ingredients: strawberry, rhubarb, hyaluronic acid (derived from marshmallow plant extract), honey, aloe vera

Cost per wear: $48 ÷ 180 wears (three months, twice daily) = $0.27 per wear

#16

Treats: pre-mature signs of aging, hyperpigmentation, loss of firmness, fine lines and wrinkles, environmental damage, collagen depletion, dullness

Key ingredients: niacinamide, amino acids, algae extract, peptides

Cost per wear: $112 ÷ 180 wears (three months, twice daily) = $0.62 per wear

#15

Treats: uneven skin tone, uneven skin texture, loss of firmness, fine lines and wrinkles, environmental damage, dullness

Key ingredients: vitamin C, vitamin E, antioxidants

Cost per wear: $102 ÷ 90 wears (three months, once daily in the morning) = $1.13 per wear

#14

Treats: hyperpigmentation, dryness, environmental damage, dullness and congestion, loss of firmness, uneven skin tone, fine lines and wrinkles

Key ingredients: kombucha blend, amino acids, hyaluronic acid, glycolic acid

Cost per wear: $80 ÷ 180 wears (three months, twice daily) = $0.44 per wear

#13

Treats: redness and inflammation, environmental damage, hyperpigmentation, large pores, dullness, acne

Key ingredients: hyaluronic acid, herbal extracts

Cost per wear: $66 ÷ 180 wears (three months, twice daily) = $0.37 per wear

#12

Treats: hyperpigmentation, large pores, fine lines and wrinkles, loss of firmness, environmental damage, acne and congestion, uneven skin texture, collagen depletion

Key ingredients: lactic acid, licorice extract, aloe vera, lemongrass

Cost per wear: $158 ÷ 90 wears (three months, once daily) = $1.76 per wear

#11

Treats: discoloration, hyperpigmentation, dullness, and a healthier skin barrier

Key ingredients: tranexamic acid, niacinamide, phenylethyl resorcinol, marine extract blend, phytic acid

Cost per wear: $154 ÷ 180 wears (three months, twice daily) = $0.86 per wear

#10

Treats: large pores, milia, inflammation/hyperpigmentation, uneven skin texture, dullness, cell regeneration, and environmental damage

Key ingredients: growth factors, glycolic acid, salicylic acid, AHA acids

Cost per wear: $179 ÷ 180 wears (three months, twice daily) = $0.99 per wear

#9

Treats: environmental damage, accelerated signs of aging, hyperpigmentation, loss of firmness

Key ingredients: resveratrol, vitamin E, niacinamide, caffeine

Cost per wear: $153 ÷ 90 wears (three months, once daily in the evening) = $1.70 per wear

#8

Treats: hyperpigmentation, dullness, environmental damage, acne, scarring, melasma

Key ingredients: tranexamic acid, kojic acid, vitamin B3

Cost per wear: $98 ÷ 180 wears (three months, twice daily) = $0.54 per wear

#7

Treats: dullness, acne, uneven skin texture, fine lines and wrinkles, hyperpigmentation, environmental damage, loss of firmness

Key ingredients: sugar cane extractsalicylic acid, mushroom extract

Cost per wear: $135 ÷ 90 wears (three months, once daily) = $1.50 per wear

#6

Treats: dehydration, dullness, fine lines and wrinkles, uneven skin texture, and loss of firmness

Key ingredients: hyaluronic acid, vitamin B5

Cost per wear: $82 ÷ 180 wears (three months, twice daily) = $0.46 per wear

#5

Treats: hyperpigmentation, discoloration, acne, fine lines, uneven skin tone, environmental damage

Key ingredients: phloretin, vitamin C, ferulic acid

Cost per wear: $166 ÷ 90 wears (three months, once in the morning) = $1.84 per wear

#4

Treats: environmental damage, hyperpigmentation, dryness, collagen depletion

Key ingredients: vitamin C, hyaluronic acid, antioxidants

Cost per wear: $127 ÷ 90 wears (three months, once in the morning) = $1.41 per wear

#3

Treats: dryness, uneven skin texture, loss of firmness, lines, and wrinkles

Key ingredients: proxylane, hyaluronic acid, and a strategic blend of licorice root and purple rice extract

Cost per wear: $98 ÷ 180 wears (three months, twice daily) = $0.54 per wear

#2

Treats: dryness, cell regeneration, hyperpigmentation, environmental damage, loss of firmness, lines, and wrinkles

Key ingredients: TNS (growth factor), peptides, and antioxidants from green tea, CoQ10, and EGT

Cost per wear: $281 ÷ 180 wears (three months, twice daily) = $1.56 per wear

#1

Treats: lines, wrinkles, dullness, dryness, hyperpigmentation, loss of firmness, and environmental damage

Key ingredients: vitamin C, vitamin E, and ferulic acid

Cost per wear: $166 ÷ 90 wears (three months, once daily) = $1.84 per wear

Next up, 28 Holy Grail Skincare Products That Cost Less Than $5 Per Wear.